Peptide · Investigational
Elamipretide
A mitochondria-targeting peptide (SS-31) in clinical trials for mitochondrial and heart disease.
Key facts
- Also known as: SS-31, MTP-131
- Status: Investigational
- Used for: Mitochondrial disease (trials)
- Natural counterpart: Synthetic; binds cardiolipin, a natural mitochondrial lipid.
- Target enzyme / receptor: Cardiolipin (inner-mitochondrial-membrane lipid) — not a receptor
- Signalling pathway: Stabilises cristae → improves electron transport & ATP production
In plain terms: Props up the mitochondrial membrane so cells make energy more efficiently. - Crystal structure: no peptide–target complex in the PDB yet — study the target ↗
Status & safety
This peptide is investigational, or approved only in some regions — it is not a general consumer product. Treat online sellers with caution and speak to a clinician.
Research & clinical studies
Explore the biochemistry and clinical evidence for Elamipretide — these open live, date-sorted searches, so they always show the latest.
Read research papers on PubMed ↗
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