Peptide · Research-only

MOTS-c

A mitochondrial-derived peptide studied for metabolism and exercise capacity; research-stage, not an approved product.

Key facts

  • Status: Research-only
  • Used for: Mitochondrial / metabolic
  • Natural counterpart: It IS a natural mitochondrial-derived peptide.
  • Target enzyme / receptor: AMPK pathway (metabolic sensor) — no classical receptor
  • Signalling pathway: Activates AMPK; nuclear translocation → metabolic & stress-response genes
    In plain terms: Flips on AMPK, the cell’s metabolic exercise-mimicking switch.
  • Crystal structure: no peptide–target complex in the PDB yet — study the target ↗

Status & safety

This is sold as an unapproved “research chemical” (labelled “not for human use”). It is not approved, is unregulated, and carries real safety and legal risks. We cover it for information, not to encourage buying or using it.

Research & clinical studies

Explore the biochemistry and clinical evidence for MOTS-c — these open live, date-sorted searches, so they always show the latest.

Read research papers on PubMed ↗

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