Peptide · Investigational

Semax

A nootropic peptide used medically in Russia for stroke and cognition; unapproved elsewhere.

Key facts

  • Status: Investigational
  • Used for: Nootropic (Russia only)
  • Natural counterpart: An analog of a natural ACTH(4-10) / melanocortin fragment.
  • Target enzyme / receptor: Melanocortin & neurotrophin systems (incompletely defined)
  • Signalling pathway: ↑BDNF/NGF expression → neuroprotection & cognitive effects (mechanism not fully established)
    In plain terms: Thought to raise brain growth factors (BDNF/NGF) supporting focus.
  • Crystal structure: no peptide–target complex in the PDB yet — study the target ↗

Status & safety

This peptide is investigational, or approved only in some regions — it is not a general consumer product. Treat online sellers with caution and speak to a clinician.

Research & clinical studies

Explore the biochemistry and clinical evidence for Semax — these open live, date-sorted searches, so they always show the latest.

Read research papers on PubMed ↗

Clinical studies (ClinicalTrials.gov) ↗ Google Scholar ↗ Related guide → All peptides & profiles →

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