Peptide · Approved

Abaloparatide

A PTH-related-protein analog (Tymlos) that builds bone in osteoporosis.

Key facts

  • Also known as: Tymlos
  • Status: Approved
  • Used for: Osteoporosis
  • Natural counterpart: An analog of natural PTH-related protein (PTHrP).
  • Target enzyme / receptor: PTH1 receptor (PTH1R) — class B GPCR
  • Signalling pathway: Gαs → cAMP → PKA → osteoblast bone formation
    In plain terms: Daily dosing signals bone-building cells to add new bone.
  • Crystal / cryo-EM structure: Available  PDB 8FLQ ↗

Status & safety

This is an approved medicine — prescription-only in most countries. Only use it under a licensed clinician, obtained through a pharmacy.

Research & clinical studies

Explore the biochemistry and clinical evidence for Abaloparatide — these open live, date-sorted searches, so they always show the latest.

Read research papers on PubMed ↗

Clinical studies (ClinicalTrials.gov) ↗ Google Scholar ↗ Related guide → All peptides & profiles →

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