Peptide · Approved
Carbetocin
A long-acting oxytocin analog (Duratocin) to prevent bleeding after childbirth.
Key facts
- Also known as: Duratocin
- Status: Approved
- Used for: Postpartum haemorrhage
- Natural counterpart: A longer-acting analog of natural oxytocin.
- Target enzyme / receptor: Oxytocin receptor (OXTR) — class A GPCR
- Signalling pathway: Gαq → PLC → Ca²⁺ → sustained uterine contraction
In plain terms: Like oxytocin but longer-lasting — keeps the uterus contracted to stop bleeding. - Crystal / cryo-EM structure: Available PDB 7RYC ↗
Status & safety
This is an approved medicine — prescription-only in most countries. Only use it under a licensed clinician, obtained through a pharmacy.
Research & clinical studies
Explore the biochemistry and clinical evidence for Carbetocin — these open live, date-sorted searches, so they always show the latest.
Read research papers on PubMed ↗
Clinical studies (ClinicalTrials.gov) ↗
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