Peptide · Approved

Desmopressin

A vasopressin analog (DDAVP) for bedwetting, diabetes insipidus and some bleeding disorders.

Key facts

  • Also known as: DDAVP
  • Status: Approved
  • Used for: Bedwetting, diabetes insipidus
  • Natural counterpart: A synthetic analog of natural vasopressin (ADH).
  • Target enzyme / receptor: V2 receptor (AVPR2) — class A GPCR
  • Signalling pathway: Gαs → cAMP → aquaporin-2 insertion → water reabsorption
    In plain terms: Tells kidney cells to reabsorb water, concentrating urine so less is passed.
  • Crystal / cryo-EM structure: Available  PDB 7KH0 ↗

Status & safety

This is an approved medicine — prescription-only in most countries. Only use it under a licensed clinician, obtained through a pharmacy.

Research & clinical studies

Explore the biochemistry and clinical evidence for Desmopressin — these open live, date-sorted searches, so they always show the latest.

Read research papers on PubMed ↗

Clinical studies (ClinicalTrials.gov) ↗ Google Scholar ↗ Related guide → All peptides & profiles →

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