Peptide · Approved

Glucagon

A pancreatic hormone that raises blood sugar; the emergency treatment for severe hypoglycaemia.

Key facts

  • Also known as: GlucaGen, Baqsimi
  • Status: Approved
  • Used for: Severe low blood sugar
  • Natural counterpart: It IS the natural hormone — from pancreatic α-cells.
  • Target enzyme / receptor: Glucagon receptor (GCGR) — class B GPCR
  • Signalling pathway: Gαs → cAMP → PKA → hepatic glycogenolysis & gluconeogenesis
    In plain terms: The opposite of insulin — tells the liver to dump stored sugar and raise blood glucose fast.
  • Crystal / cryo-EM structure: Available  PDB 5YQZ ↗

Status & safety

This is an approved medicine — prescription-only in most countries. Only use it under a licensed clinician, obtained through a pharmacy.

Research & clinical studies

Explore the biochemistry and clinical evidence for Glucagon — these open live, date-sorted searches, so they always show the latest.

Read research papers on PubMed ↗

Clinical studies (ClinicalTrials.gov) ↗ Google Scholar ↗ Related guide → All peptides & profiles →

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