Peptide · Investigational
Kisspeptin
A hypothalamic peptide central to puberty and fertility, under clinical investigation for reproductive medicine.
Key facts
- Also known as: KP-54, metastin
- Status: Investigational
- Used for: Reproductive hormone (trials)
- Natural counterpart: It IS a natural hormone (KISS1 gene product) that triggers GnRH.
- Target enzyme / receptor: KISS1 receptor (GPR54 / KISS1R) — GPCR
- Signalling pathway: Gαq → PLC → triggers GnRH release → LH/FSH
In plain terms: The upstream trigger that starts the whole reproductive hormone cascade. - Crystal structure: no peptide–target complex in the PDB yet — study the target ↗
Status & safety
This peptide is investigational, or approved only in some regions — it is not a general consumer product. Treat online sellers with caution and speak to a clinician.
Research & clinical studies
Explore the biochemistry and clinical evidence for Kisspeptin — these open live, date-sorted searches, so they always show the latest.
Read research papers on PubMed ↗
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