Peptide · Approved

Octreotide

A somatostatin analog (Sandostatin) that suppresses growth hormone and hormone-secreting tumours.

Key facts

  • Also known as: Sandostatin
  • Status: Approved
  • Used for: Acromegaly, tumours
  • Natural counterpart: Mimics somatostatin, the body’s own hormone off-switch.
  • Target enzyme / receptor: Somatostatin receptors SSTR2/SSTR5 — GPCRs
  • Signalling pathway: Gαi → ↓adenylate cyclase → ↓cAMP → inhibited hormone secretion
    In plain terms: Acts as an off-switch, quieting growth-hormone and other hormone release.
  • Crystal / cryo-EM structure: Available  PDB 7XAU ↗

Status & safety

This is an approved medicine — prescription-only in most countries. Only use it under a licensed clinician, obtained through a pharmacy.

Research & clinical studies

Explore the biochemistry and clinical evidence for Octreotide — these open live, date-sorted searches, so they always show the latest.

Read research papers on PubMed ↗

Clinical studies (ClinicalTrials.gov) ↗ Google Scholar ↗ Related guide → All peptides & profiles →

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