Peptide · Approved

Teriparatide

A parathyroid-hormone fragment (Forteo) that builds new bone in severe osteoporosis.

Key facts

  • Also known as: Forteo
  • Status: Approved
  • Used for: Osteoporosis (PTH 1-34)
  • Natural counterpart: The active 1-34 fragment of natural parathyroid hormone (PTH).
  • Target enzyme / receptor: PTH1 receptor (PTH1R) — class B GPCR
  • Signalling pathway: Gαs → cAMP → PKA (and Gq/PLC) → osteoblast bone formation
    In plain terms: Given in daily pulses, it tips the balance toward building new bone.
  • Crystal / cryo-EM structure: Available  PDB 7Y36 ↗

Status & safety

This is an approved medicine — prescription-only in most countries. Only use it under a licensed clinician, obtained through a pharmacy.

Research & clinical studies

Explore the biochemistry and clinical evidence for Teriparatide — these open live, date-sorted searches, so they always show the latest.

Read research papers on PubMed ↗

Clinical studies (ClinicalTrials.gov) ↗ Google Scholar ↗ Related guide → All peptides & profiles →

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